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Raman Spectroscopy for Ultra-Sensitive Salivary Diagnosis and Radiotherapy Treatment Monitoring of Oral Cancer

Molecular and Biomolecular Physics Department

National Institute for Research and Development of Isotopic and Molecular Technologies

2. Protocol for saliva samples collection, transport, and storage:

· Collect saliva samples using the passive drool technique;

· Samples are centrifuged to remove oral impurities, including epithelial cells and food residues, and the supernatant is collected;

· Transport samples to the lab.

Objective 1 Establish the biomolecular composition of healthy saliva

 

1.1  Determine an appropriate protocol for the collection, transport, and storage of the saliva samples  - Scientific report

1. Literature study

· Investigate the methods used for saliva collection and samples preparation;

· Raman and SERS measurement conditions and data analysis;

· Evaluate the identified salivary biomarkers specific to oral cancer.