The preparation of thin gold layers deposited on mica, gold nanoparticles and
bithiophene-phenothiazine podands
AI.1 Gold thin layers
deposition on mica / Coordinator
AI.2 Preparation of gold
nanoparticles / Coordinator
AI.3 Design and
synthesis of podands and of their precursors; elaboration of synthesis protocols /
Partner 1
AI.4. Characterisation of gold surfaces morphology and of the gold nanoparticles dimension by
AI.5. Numerical
simulations of the NMR spectra for podands and bithiophene-phenothiazine macrocycles
/ Coordinator
AI.6. Identification
of podands macrocyclization conditions and of the template effect of various cations by
molecular modelling methods / Partener 3
AI.7. Determination if
the redox properties of podands by cyclic voltametry / Coordinator
AI.8. Analysis of
fluorescence properties for thiophene-phenothiazine podands and the identification of
fluorescence vanishing conditions
/ Partner 2
AI.9. Structural
analysis of the podands and of the various bithiophene-phenothiazine macrocycles by NMR and
mass spectroscopy
/ Partener 1
AI.10. Results dissemination/ Coordinator, Partner 1, Partner 2
Stage IISelf-assembled Bidimensional Supramolecular Structures (SBSS) of bithiophene- phenothiazine
podands deposited on gold surfaces and gold nanoparticles by mercaptoalkyl units
AII.2. The investigation of the possible effects of self-assembly into SBSS on the spectral features of the bithiophene- phenothiazine podands. IR and UV/VIS spectroscopy / Coordinator
AII.5. Determination of the redox properties of SBSS by cyclic voltametry /Coordinator
AII. 7 The acquisition, installation and testing of the fluorescence spectrometer / Coordinator
AII.8. Investigation of fluorescent properties of SBSS and identification of the fluorescence vanishing conditions by fluorescence spectroscopy / Coordinator
AII.9. Results dissemination / Coordinator
Stage IIISSBS with phenothiazine podands deposited on gold surfaces and nanoparticles via N-mercaptoalkyl units
1. The synthesis of phenothiazine macrocycles with polyethylen glycol chains, and of the phenothiazine and bi-thiophen macrocycles with azobenzen units, respectively, and the design of the synthesis protocol / Partner 1 + Partner E (AIII.1 si AIII.2)
2. The preparation of SBSS by depositing the podands and the macrocycles, respectively, on gold surfaces Au (111) and gold nanoparticles, respectively / Partner 1 (AII.1 si AIII.9)
3. The investigation of the morfology of SBSS and the estimation of their degree of order by atomic force microscopy / Partner 1 (AII.4 si AIII.10)
4. The identification of the geometrical structure of the podands and of the phenothiazine macrocycles, free or attached to gold surfaces, through methods of molecular modeling / Partner 3 (AII.3 si AIII.4)
5. The investigation of the structural changes of SBSS induced by the pH change and/or by complexation with various cations and/or by inducing the photo-isomeristion of the azobenzenic component/ Partner 1 (AII.6 si AIII.12)
6. The determination of the redox properties of the macrocycles and of the SBSS, respectively, by cyclic voltametry / Coordinator (AIII.6 si AIII.11)
7. The numerical simulation of NMR spectra for the synthetized macrocycles and their structural analysis by: mass spectroscopy, NMR, UV-Vis spectroscopy, and X-ray diffraction / Coordinator (AIII.3 si AIII.5)
8. The determination of the strucural changes (cis-trans isomerisation) in macrocycles with azobenzene induced by UV–visible radiation. FT-IR and UV-Vis spectrometry / Coordinator (AIII.7)
9. The determination of the properties of complexation for the synthesized macrocycles and of the structural changes (cis-trans isomerisation) induced by UV – visible radiation in compounds with azobenzene. NMR and ESI-MS spectrometry / Partner 1 + Partner E (AIII.8)
10. The investigation of the fluorescence properties of the macrocycles in solution and, respectively, auto-assembled in SBSS and of the conditions of fluorescence quenching by : fluorescence spectroscopy / Coordinator; Fluorescence microscopy/ Partner 2 (AIII.13)
11. Results dissemination/ Coordinator, Partner 1, Partner 2, Partner 3 (AIII. 14)
Stage IV
1. The acquisition, the installation and the testing of an Isothermal Titration Calorimeter (ITC) / Coordinator (AI.10)
2. The investigation of the geometrical structure of the phenothiazine macrocycles through molecular modeling methods / Partner 3, Coordinator (AIV.3 si AV.2)
3. Preparation of the phenothiazine macrocycles with two mercaptomethyl units and of their intermediaries (podands) / Partner 1, Partner E (AIV.1, AIV.2, AIV.4, AIV.9, AV.1, AV.3, AV.4)
4. The physico-chemical and structural analysis of the phenothiazine macrocycles compounds and the investigation of the induced changes by complexation with various cations / Coordinator, Partner 2 (AIV.2, AIV.4, AIV.5, AIV.9, AIV.10, si AV.3-5)
5. The preparation of SBSS by depositing the phenothiazine macrocycles compunds on gold surfaces (111) and gold nanoparticles, respectively / Partner 1 (AIV.6.; AV.6)
6. The investigation of the morphology and of the physico-chemical and structural properties of SBSS / Coordinator, Partner 1 (AIV.6.; AV.6)
7. Results dissemination / Coordinator, Partner 1, Partner 2, Partner 3 (AIV.11)