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Dezvoltarea nanocompozitelor bazate pe nanoparticule magnetice \u0219i molecule fluorescente este un domeniu de cercetare cu dezvoltare rapid\u0103 \u00een nanotehnologie. Cu toate acestea, aceste tipuri de materiale au unele dificult\u0103\u021bi \u0219i provoc\u0103ri care trebuie dep\u0103\u0219ite, cum ar fi stingerea entit\u0103\u021bii fluorescente de c\u0103tre miezul magnetic. De aceea, sistemele de acoperire au primit o importan\u021b\u0103 deosebit\u0103 prin influen\u021ba asupra hidrofilicit\u0103\u021bii corelat\u0103 de o bun\u0103 dispersibilitate sau \u00eembun\u0103t\u0103\u021birea biocompatibilit\u0103\u021bii.<\/p>\n
Ca strat de acoperire, polidopamina \u00eendepline\u0219te aceste calit\u0103\u021bi fiind investigat\u0103 intens prin studiile in vivo<\/em> \u0219i in vitro<\/em> pentru multe aplica\u021bii biomedicale. Dar, \u00een ceea ce prive\u0219te fluorescen\u021ba, aceasta este o ni\u0219\u0103 ce se concentreaz\u0103 mai mult pe oxidare, degradare, conjugare \u0219i carbonizarea dopaminei \/ polidopaminei.<\/p>\n \u00cen acest proiect propunem o abordare diferit\u0103, prin sinteza de noi analogi ai polidopaminei cu heteroatomi suplimentari \u00een structura lor. Pentru acest tip de analogi sintetici vom studia sistematic mecanismul de polimerizare, aderen\u021ba \u0219i modul \u00een care prezen\u021ba heteroatomilor de tip N le \u00eembun\u0103t\u0103\u021be\u0219te proprietatea de fluorescen\u021b\u0103.<\/p>\n Acoperind nanoparticulele magnetice de dimensiuni uniforme cu noile materiale fluorescente vor fi proiectate nanocompozite fluorescent-magnetice, care pot servi drept instrumente terapeutice \u0219i de diagnostic, cu avantajul suplimentar de a fi u\u0219or de controlat \u0219i monitorizat prin microscopia de fluorescent\u0103.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" AbstractDezvoltarea nanocompozitelor bazate pe nanoparticule magnetice \u0219i molecule fluorescente este un domeniu de cercetare cu dezvoltare rapid\u0103 \u00een nanotehnologie. Cu toate acestea, aceste tipuri de materiale au unele dificult\u0103\u021bi \u0219i provoc\u0103ri care trebuie dep\u0103\u0219ite, cum ar fi stingerea entit\u0103\u021bii fluorescente de c\u0103tre miezul magnetic. De aceea, sistemele de acoperire au primit o importan\u021b\u0103 deosebit\u0103 prin […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-146","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/pages\/146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/comments?post=146"}],"version-history":[{"count":3,"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/pages\/146\/revisions"}],"predecessor-version":[{"id":183,"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/pages\/146\/revisions\/183"}],"wp:attachment":[{"href":"https:\/\/www.itim-cj.ro\/PNCDI\/bright-surf\/wp-json\/wp\/v2\/media?parent=146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}