Raman Spectroscopy for Ultra-Sensitive Salivary Diagnosis and Radiotherapy Treatment Monitoring of Oral Cancer

Molecular and Biomolecular Physics Department

National Institute for Research and Development of Isotopic and Molecular Technologies

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· Scientific papers:

1. A. Falamas, C. I. Faur, M. Baciut, H. Rotaru, M. Chirila, S. Cinta Pinzaru, M. Hedesiu, “Raman spectroscopic characterization of saliva for the discrimination of oral squamous cell carcinoma”, Analytical Letters, 2020, DOI: 10.1080/00032719.2020.1719129

2. A. Falamas, H. Rotaru, M. Hedesiu,  “Surface Enhanced Raman Spectroscopy (SERS) Investigations of Saliva for Oral Cancer Diagnosis”, Lasers in Medical Science, 2020, DOI: 10.1007/s10103-020-02988-2

3. A. Falamas, C.I. Faur, S. Ciupe, M. Chirila, H. Rotaru, M. Hedesiu, S. Cinta Pinzaru, “Oral and oropharyngeal cancer biomarkers for rapid and noninvasive diagnostic from micro-Raman and FT-IR spectra of saliva”, Spectrochimica Acta A: Molecular and Biomolecular Spectroscopy, under review, 2020

4. Cosmin Ioan Faur, Alexandra Falamas, MagdalenaChirila, Rares Roman, Horatiu Rotaru, Madalina Moldovan (Lazar), Silviu Albu, Ioana Robu, Mihaela Hedesiu, “Raman spectroscopy in head and neck cancer: basic principles, Raman spectra and clinical applications”, Journal of Cancer Research and Clinical Oncology , under review, 2020

 

· Conferences:

1. Processes in Isotopes and Molecules, PIM 2019, Cluj-Napoca, România, 25-27.09.2019, poster presentation: A. Falamas, M. Hedesiu, “Surface Enhanced Raman Spectroscopy (SERS) Investigations of Saliva for Oral Cancer Diagnosis”

2. Conferința Națională de Biofizică CNB 2020, 14-16 Iunie, online oral presentation: Raman Spectroscopic Characterization of Saliva for the Discrimination of Oral Squamous Cell Carcinoma

3. “VIII Ciamician Photochemistry School”, Bologna, Italy, 10-14.06.2019

 

· Other results:

1. Method for preparing the saliva samples for Raman measurements

2. Method for oral cancer diagnosis based on the micro-Raman and FT-IR signal