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Results


1st ROMANIAN - SOUTH AFRICAN SYMPOSIUM
"Cyclodextrin Inclusion Complexes"
October 13 - 14, 2008
INCDTIM Cluj-Napoca, Romania
SCIENTIFIC PROGRAM

Monday, October 13

 

930 Seminar opening
940 - 1000 S. I Farcas "Study of new cyclodextrin inclusion compounds with application in gastrointestinal tract disorders"
1000 - 1020 Mino R. Caira"X-ray structural studies of cyclodextrins and their inclusion compounds with biologically active guests"
1020 - 1040 Dyanne Cruikshank"The inclusion of agrochemicals in cyclodextrins"
1040 - 1110 Coffee break
1110 - 1130 R. Bettini"Drug/cyclodextrins interactions compound obtained by microwave drying"
1130 - 1150 I. Bratu "Inclusion compounds of some cardiovascular drugs with B - CD"
1200 - 1300 "Molecular and Biomolecular Systems" Dept. visit
1300 - 1500 LUNCH

 

Tuesday, October 14

 

1020 - 1040 M. Bogdan"Preliminary spectroscopic and spectrophotometric studies of cyclodextrin complexes with some methoxyacetophenones"
1040 - 1100 C.G. Floare "Low field NMR investigation of an unusual phase transition"
1100 - 1130 Coffee break
1130 - 1300 Round table. Conclusions
1300 - 1500 LUNCH

Research student exchange

Ms. Dyanne Cruickshank – 2 months working stage (Oct. – Nov. 2008) in the High Resolution NMR
Spectroscopy laboratory, INCDTIM , Cluj-Napoca

Subject:

Inclusion complexes of Cycluron with some native cyclodextrins studied by NMR

molecula 1 molecula 2

2nd ROMANIAN - SOUTH AFRICAN SYMPOSIUM
"Cyclodextrin Inclusion Complexes"
September 18 - 23, 2009
Sovata, Romania

The 2nd RO – SA Symposium on Cyclodextrin Inclusion Complexes is organized in the frame of joint research project between INCDTIM Cluj-Napoca, Romania and Department of Chemistry, University of Cape Town, South Africa.
This symposium will focus on recent work in the field of cyclodextrin inclusion complexes, conducted by the two partners.

 

Program

Friday, September 18

 

1830 - 1830 Dr. Floare Calin "Advances in Computational Studies of Molecular Inclusion Compounds and Proteins"
1900 Dinner

Saturday, September 19

 

1000 Trip to Praid and Sighisoara
2000 Dinner

Sunday, September 20

 

1000 Trip to Lacul Rosu
2000 Dinner

Monday, September 21

 

1030 - 1100 Prof. Mino R. Caira“Update on progress in solid-state cyclodextrin research activities”
1100 - 1130 Dr. Mihaela Mic“Characterization of β-cyclodextrin inclusion complex with vanillin by 1H NMR and ITC”
1130 - 1200 Coffee break
1200 - 1230 Dr. Ioan Bratu “Inclusion molecular processes of benzocaine in β-cyclodextrin”
1230 - 1300 Dr. Irina Kacso “Spectroscopic investigation of the interaction between β-cyclodextrin and vitamin B10”
1300 Lunch
1900 Dinner

 

Tuesday, September 22

 

1030 - 1100 Prof. Elba Bujan "Effect of cyclodextrins on the reactivity of organophosphorous insecticides"
1100 - 1130 Dr. Mircea Bogdan "1H NMR spectroscopic characterization of inclusion complex comprising β-CD and tolfenamic acid"
1130 Coffee break
1200 - 1230 Ms. Lee Trollope "Cyclodextrin inclusion of antioxidants and related drugs"
1230 - 1300 Dr. Sorin Farcas "Inclusion Study of Resveratrol in Natural Cyclodextrin (Liquid Phase)"
1330 Lunch
1930 Dinner

Research exchanges

Mr. Vincent Smith: (02.07 – 30.07.2009) Research exchanges

Subject:

Inclusion complexes of "Cyclodextrin inclusion of phenylurea as studied by NMR"

molecula 1

a) α-CD           b) β-CD
R1 = H, Br, Cl           R2 = CH3, OCH3

Ms. Lee Trollope: (02.09 – 17.10.2009) in the NMR laboratory, INCDTIM , Cluj-Napoca

Subject:

"NMR investigation of the inclusion complex between native cyclodextrins and a class of acetophenones"

Dr. Mircea Bogdan and Dr. Adrian Pirnau
(01 – 15. 12.2009) in the Supramolecular Chemistry Center, Univ. Cape Town

Subject:

The analysis of the obtained results during 2009
Lecture presented: 1H NMR spectroscopic characterization of inclusion complexes of tolfenamic and flufenamic acid with β-CD

 



3rd ROMANIAN - SOUTH AFRICAN SYMPOSIUM
"Cyclodextrin Inclusion Complexes"
October 9 - 14, 2010
Moeciu, Romania

The 3rd RO – SA Symposium on Cyclodextrin Inclusion Complexes is organized in the frame of a joint research project between INCDTIM Cluj-Napoca, Romania and Department of Chemistry, University of Cape Town, South Africa.
This Symposium will focus on recent work in the field of cyclodextrin inclusion complexes, conducted by the two partners.

 

Program

Saturday, October 9

 

1000 Departure to Moeciu
1900 Dinner

Sunday, October 10

 

830 - 930 Breakfast
1000 Trip to Bran and Poiana Brasov
2000 Dinner

Monday, October 11

 

830 - 930 Breakfast
1000 Trip to Peles Castle
2000 Dinner

Tuesday, October 12

 

830 - 930 Breakfast
1030 - 1100 Prof. Mino R. Caira"XRD studies of derivatised cyclodextrins and their inclusion complexes: a mini-review 2005-2009"
1100 - 1130 Dr. Mihaela Mic"Nanocalorimetric study of host-guest complexation of two cardiovascular drugs with cyclodextrins"
1130 - 1200 Coffee break
1200 - 1230 Dr. Ioan Bratu "β-cyclodextrin and chitosan as drug-carriers for some fluoroquinolones"
1230 - 1300 Dr. Irina Kacso "Inclusion of Caffeic acid in β-cyclodextrin. Solid and liquide state interactions"
1330 - 1500 Lunch
1600 - 1800 Discutions
1900 Dinner

 

Wednesday, October 13

 

830 - 930 Breakfast
1030 - 1100 Prof. Helena Dodziuk "Modeling of Molecular and Chiral Recognition by Cyclodextrins"
1100 - 1130 Dr. Mircea Bogdan "1H NMR study of the inclusion complex between β-CD and flurbiprofen"
1130 Coffee break
1200 - 1230 Drd. Emile Engel "Supramolecular modification of antiretroviral drugs"
1230 - 1300 Dr. Calin Floare "Experimental and theoretical analysis of the encapsulation in cyclodextrins and self-association of Vanillin"
1330 - 1500 Lunch
1600 - 1800 Discutions
1930 Dinner

Thursday, October 14

 

830 - 930 Breakfast
1000 Departure to Cluj-Napoca

Research exchanges

Mr. Emile Engel (06.10 – 01.12.2010) in the NMR laboratory, INCDTIM , Cluj-Napoca

Subject:

"NMR investigations of some antiretroviral drugs with native and derivatized cyclodextrins"

 

Publications list (2008-2010)

  1. M. Bogdan, A Pirnau, C. Floare, Carmen Bugeac
    Binding interaction of indomethacin with human serum albumin J. Pharm. Biomed. Anal. 47, 981 (2008)
  2. A. Pîrnau, M. Bogdan
    “Investigation of the interaction between naproxen and HSA” Rom. J. Biophys.18 (1), 49-55 (2008)
  3. E. de Vries, M. Caira, M. Bogdan, S.I. Farcas, Diana Bogdan,
    Inclusion of Parabens in ß-cyclodextrin: A Solution NMR and X-ray Structural Investigation Supramol. Chem 21 (5), 358-366 (2009)
  4. M. Bogdan, C.G. Floare, A. Pirnau
    1H NMR investigation of self-association of vanillin in aqueous solution J. of Phys.Conf. Series (JPCS)
    182, 012002, 1-5 (2009)
  5. A. Pirnau, M. Bogdan, C.G. Floare
    NMR spectroscopic characterization of β-cyclodextrin inclusion complex with vanillin J. of Phys.Conf. Series (JPCS) 182, 012013, 1-5 (2009)
  6. Mihaela Mic, Dyanne Cruickshank and I. Turcu,
    Assessment of molecular interaction in a cycluron-cyclodextrin inclusion Journal of Physics: Conference Series (JPCS) 182, 012011 (2009)
  7. L.Szabo, V. Chis, A Pirnau, N. Leopold, O. Cozar, Sz. Orosz
    Spectroscopic and theoretic study of amlodipine besylate J. Mol. Struct., 924-926, 385 – 392 (2009)
  8. A. Pirnau, V. Chis, L. Szabo, O. Cozar, M. Vasilescu, O. Oniga, R.A. Varga
    Experimental and theoretical investigation of 5-para-nitro-benzylidene-thiazolidine-20thione-4-one molecule J. Mol. Struct., 924-926, 361 – 370
  9. I. Bratu, Marieta Muresan-Pop, Irina Kacso, S.I. Farcas (2009)
    Spectroscopic investigation of the interaction between β-cyclodextrin and ascorbic acid Journal of Physics: Conf. Series 182, 012004, 1-5 (2009)
  10. Gh. Borodi, Irina Kacso, S.I. Farcas, I. Bratu
    Inclusion compound of vitamin B6 in ß-CD. Physico-chemical and structural investigations Journal of Physics: Conf. Series 182, 012003, 1-5 (2009)
  11. Irina Kacso, Gh. Borodi, S.I. Farcas, I. Bratu
    Inclusion compound of vitamin B13 in β-cyclodextrin. Structural investigations Journal of Physics: Conf. Series 182, 012009, 1-5 (2009)
  12. S.I.Farcas, I.Bratu,Irina Kacso, gh. Borodi, M. Bogdan
    Solid and liquid state inclusion complexes of some gastrointestinal drugs with β-cyclodextrin Rev. Chimie (in press)
  13. V. Smith, Diana Bogdan, Mino R. Caira, M. Bogdan, Susan A. Bourne, S.I. Farcas
    Cyclodextrin inclusion of four phenylurea herbicides: determination of complex stoichiometries and stability constants using solution NMR spectroscopy Supramol. Chem. 22, (3), 172-177 (2010)
  14. Irina Kacso, Gh. Borodi, S.I. farcas, A. Hernanz, I. Bratu
    Host-guest system of vitamin B10 in β-cyclodextrin: characterization of the interaction in solution and in solid state J. Incl. Phenom. Macrocycl. Chem., 68, 175-182 (2010)
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